Remember Me - Johnny Greenteeth
The best way to defeat him is to use your S-Pressens skills, first go with Logic Bomb to take out the leapers & then quickly switch to Sensen DOS to stun the remaining leapers if any & Johnny. Then go for Sensen Fury & pummel Johnny.
You will need to use the above strategy a few times before you initiate Johnny's destruct sequence.
I always pause the game by pressing select to modify my combos depending on if I need healing or to recharge my S-Pressens.